A new 22 country survey of the Presidential candidates shows that respondents prefer Obama to McCain by a margin of 4 to 1.
Writing in the left-wing British daily, Freedland described "a sinking feeling in the stomach" that the Democrats are "about to lose an election they should win.
"But what of the rest of the world? This is the reaction I fear most," Freedland wrote.
"Until now, anti-Americanism has been exaggerated and much misunderstood: outside a leftist hardcore, it has mostly been anti-Bushism, opposition to this specific administration.
"But if McCain wins in November, that might well change, for it will have been the American people, not the politicians, who will have passed up a once-in-a-generation chance for a fresh start – a fresh start the world is yearning for."